CLINICAL MICROBIOLOGY AND VIROLOGY

A.A. di erogazione 2020/2021
Insegnamento obbligatorio

Laurea Magistrale in BIOMEDICAL SCIENCES
 (A.A. 2020/2021)
L'insegnamento è condiviso, tecnicamente "mutuato" con altri corsi di laurea, consultare il dettaglio nella sezione Mutuazioni
Anno di corso: 
1
Tipologia di insegnamento: 
Affine/Integrativa
Settore disciplinare: 
MICROBIOLOGIA E MICROBIOLOGIA CLINICA (MED/07)
Lingua: 
Inglese
Crediti: 
6
Ciclo: 
Secondo Semestre
Ore di attivita' frontale: 
48
Dettaglio ore: 
Lezione (48 ore)

The course aims at providing a complete overview of the major infections agents of medical interest, to understand the alterations that may cause infectious diseases.
Critically review the laboratory investigations and methods available in routine laboratories and new approaches, such as molecular biology techniques and MALDI-TOF, to diagnose infectious diesease through the recognition of pathogenic agent.
On successful completion of this module, the learner will be able to: Identify the laboratory approach for the evaluation of infectiuos disease. Identify the critical step in the laboratory investigations such as specimen sampling and transport. Identify the principles and evaluate the biochemical methodologies used for the isolation of specific microorganisms. Identify and appraise the hierarchical methods to be used in complex pipelines for microroganism identification. To evaluate the importance of the clinical presentation of the infectious disease leading to the use of the most appropriate laboratory method to diagnose the disease. Demonstrate the use of various laboratory instruments and equipment.
Applying knowledge and understanding (Skills and know how).
Be able to apply the methods to analyze the specimen used in microbiological laboratory as blood, urine, SCF in order to identify specific agents of pathology. Be able to employ the acquired notions to select specific list of exams to use for a complete diagnostic procedure and to select the appropriate technologies.

Students are expected to be familiar with general microbiology skills and principles .

1.BACTERIOLOGY

I.INTRODUCTION
II. OVERVIEW OF THE LABORATORY’S ROLE IN THE DIAGNOSIS OF BACTERIAL INFECTIONS
III. ROAD TO BACTERIAL IDENTIFICATION
IV. SEQUENCING
V. MATRIX-ASSISTED LASER DESORPTION IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY (MALDI-TOF MS) FOR BACTERIAL IDENTIFICATION
VI. BASICS OF BACTERIAL IDENTIFICATION BY MALDI-TOF MS
VII. CLINICAL SYNDROMES

2.ANTIMICROBIAL SUSCEPTIBILITY TESTING

I. INTRODUCTION
II. KEY ANTIBACTERIAL AGENTS USED IN CLINICAL PRACTICE
III. PERFORMANCE OF ANITIMICROBIAL SUSCEPTIBILITY TEST
IV. ANTIMICROBIAL RESISTANCE AND TESTING CONSIDERATIONS FOR KEY BACTERIAL PATHOGENS
V. ANTIMICROBIAL RESISTANCE AND TESTING CONSIDERATIONS FOR MYCOBACTERIA AND AEROBIC ACTINOMYCETES
VI. SUSCEPTIBILITY TESTING OF CANDIDA SPECIES

3.MYCOBACTERIOLOGY

i. INTRODUCTION AND OVERVIEW OF MYCOBACTERIA
ii. CLASSIFICATION OF MYCOBACTERIA AND CLINICAL SIGNIFICANCE
iii. LABORATORY METHODS
iv. CONCLUSIONS AND FUTURE DIAGNOSTIC DEVELOPMENTS

4.MYCOLOGY

INTRODUCTION
MANUALS AND GUIDELINES
GLOSSARY OF MYCOLOGIC TERMS
ABBREVIATIONS
FUNGAL TAXONOMY AND NOMENCLATURE
EPIDEMIOLOGY OF FUNGAL INFECTIONS
LABORATORY DIAGNOSIS OF FUNGAL INFECTIONS: AN INTRODUCTION
LABORATORY DIAGNOSIS: PREANALYTICAL PHASE
LABORATORY DIAGNOSIS: ANALYTICAL PHASE
LABORATORY DIAGNOSIS: POSTANALYTICAL PHASE
ANTIFUNGAL AGENTS
INTRODUCTION TO FUNGAL INFECTIONS
BLOODSTREAM INFECTIONS AND ENDOCARDITIS
RESPIRATORY TRACT INFECTIONS
CENTRAL NERVOUS SYSTEM INFECTIONS
BONE AND JOINT INFECTIONS
INTRAABDOMINAL INFECTIONS
GASTROINTESTINAL INFECTIONS
URINARY TRACT INFECTIONS
GENITAL INFECTIONS
EYE INFECTIONS
EAR INFECTIONS
SKIN, HAIR, AND NAIL INFECTIONS
SUBCUTANEOUS INFECTIONS
MICROSPORIDIOSIS AND RARE INFECTIONS

5.PARASITOLOGY

I. INTRODUCTION
II. PARASITE CLASSIFICATION AND TAXONOMY
III. LABORATORY METHODS
IV. BLOOD AND TISSUE PROTOZOA
V. INTESTINAL AND UROGENITAL PROTOZOA AND MICROSPORIDIA
VI. INTESTINAL HELMINTHS
VII. BLOOD AND TISSUE HELMINTHS
VIII. MEDICALLY IMPORTANT ARTHROPODS
IX. DELUSIONAL PARASITOSIS

6.VIROLOGY

I. INTRODUCTION AND HISTORICAL PERSPECTIVE
II. VIRAL INFECTIONS OF THE RESPIRATORY TRACT
III. VIRAL INFECTIONS IN IMMUNOCOMPROMISED POPULATIONS
IV. SEXUALLY TRANSMITTED INFECTIONS
V. VIRAL INFECTIONS OF THE CENTRAL NERVOUS SYSTEM
VI. VIRAL GASTROENTERITIS
VII. VIRAL HEPATITIS
VIII. REEMERGING VACCINE-PREVENTABLE VIRAL ILLNESS
IX. SUMMARY AND CONCLUSION

Lectures based on the use of power points presentations and video projections.

Oral exams, the minimum to pass the exam is 18/30. During the exam the student will be evaluated considering his knowledge and understanding ( 25 % ), the ability to apply knowledge and understanding ( 25 % ) , his independent judgment ( 15 % ), the communication skills ( 15 % ) and the ability to learn ( 20 % ) in relation to curse program.

Tietz textbook of clinical chemistry and molecular biology, 6th edition
Jawetz, Melinick and Adelberg’s medical microbiology, 28th edition
Koneman’s Color Atlas and Textbook of Diagnostic Microbiology, 7th edition

For student reception, make an appointment via email with the teachers.
Student Reception: appointment by e-mail (francesco.pallotti@uninsubria.it).

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Seleziona l‘anno in cui ti sei immatricolato e troverai le informazioni relative all'insegnamento del tuo piano di studio.

A.A. 2021/2022

Anno di corso: 1
Curriculum: Basic and applied biomedical sciences
Anno di corso: 1
Curriculum: Double Degree Programme

A.A. 2020/2021

Anno di corso: 1
Curriculum: Basic and applied biomedical sciences

A.A. 2019/2020

Anno di corso: 1
Curriculum: Double Degree Programme
Anno di corso: 1
Curriculum: Basic and applied biomedical sciences