ADVANCED CLINICAL IMMUNOLOGY I
- Scheda dell'insegnamento
- Obiettivi formativi
- Metodi didattici
- Verifica dell'apprendimento
Lectures: The students will have a comprehensive overview about the immune system and some immunological diseases. In particular, they will be able to define immunodeficiencies like SCID, X-linked immunological diseases, AIDS, allergies and related genetics.
Seminars: The students will be able to work with “model systems” to analyze diseases. They will learn how to write grants and understand the basics of the finances required for immunological assays and research.
Lectures: The lectures will teach the students the fundamentals in cellular (development of lymphocytes in the bone marrow and thymus, differentiation and activation of leucocytes, leucocytes during immune responses) and molecular immunology (signal cascades, development of BCR and TCR, marker genes, homing). They will learn the basics of experimental work (relevant technologies e.g. knock-out, knock-in, conditional knock-out, regulatory cells, antibody and recombinant immunological molecules for therapies and experimental approaches. They will learn the basis of important immunological diseases.
Seminars: In the seminars the students will either present and discuss the scientific literature about an immunological mouse model, or prepare grants about a defined subject.
Lectures and seminars
The final exam will also include an evaluation of the students’ performance in the Laboratory module “Advanced and Clinical Immunology II”. Written exam 60%; Protocol practical course 30%; grant/presentation 10%
Janeway Immunobiology, Garland Science, last edition
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